For a high-school English class, I was tasked with creating my interpretation of the "To Be or Not To Be" soliloquy from Hamlet. I think the teacher intended us to create some kind of artwork or video adapation; I created a game. Specifically, a rhythm game.
The game itself is more gimmick than gameplay, as the purpose it was intended to fulfill is "to make people laugh when I presented it in class" (which is a purpose it did well at). It is, however, significant in my game development career as it is the first project I ever released that I made in Unity.
More details on the game can be found in my blog post about it.